International Journal of Pediatric Dermatology

Reticular Pigmentary Anomalies in Pediatrics

Maria Isabel Pastura — 2025-03-07

Reticular pigmentary anomalies in childhood consists of different entities that clinically present with a common factor of a hyperpigmented reticular skin pattern. This is why they are particularly perplexing for the dermatologist in their daily practice. However, they differ from each other in terms of their age of onset, predominant location, preferred ethnicity, evolution, associated systemic involvement, distinctive histopathological and molecular characteristics, and their therapeutic response.

A clinical case about a teenage male diagnosed with Dowling-Degos Disease, evaluated at the Pediatric Dermatology Service of Dr. Ricardo Gutiérrez Children's Hospital is reported as an example.

International Panel Expert on “Photoprotection in pediatric age”. March, 01, 2025. Guglielmo Marconi University of Rome, Italy

Fabio Arcangeli — 2025-04-14

Terra Firma-Forme Dermatosis (TFFD)

Antonio Iannone — 2025-06-12

The authors report the case of a 4-month-old child of Moroccan origins affected by pigmentary dermatitis extending to the body and limbs whose clinical and dermoscopic characteristics allowed a hypothetical diagnosis of Terra Firma Forme Dermatosis. Rubbing with 70 % isopropyl alcohol caused the lesions to disappear, confirming the diagnosis. This condition, whose origin is still not well understood, is decidedly rare in the first months of life.

Breaking Capillaries: An Unusual Rash in Human Metapneumovirus Infection

Jessica Wright — 2025-10-23

Human metapneumovirus (hMPV), an established cause of bron-chiolitis in infants, has not been previously associated with signi-ficant cutaneous findings. We describe a case of an infant with hMPV infection who presented with a cephalocaudal rash and pe-techiae. Dermatologic evaluation revealed signs consistent with the Rumple-Leede phenomenon. This case highlights the impor-tance of recognizing pressure-induced purpura in the context of viral illness. Recognition of this benign pressure induced purpura will avoid unnecessary workup and isolation precautions.

Five Cases of Pediatric Cutaneous Mastocytosis and Autism Spectrum Disorder

Theoharis Theoharides — 2025-10-15

Here we report five cases of children with both Cutaneous Mastocytosis (CM), a pediatric condition of skin lesions containing mast cells, and autism spectrum disorder (ASD), a neurodevelopmental condition characterized by impaired communication and obsessive behaviors. This apparent comorbidi-ty is intriguing given that the co-occurrence of these two conditions would be expected to be infrequent in the general population. The possible asso-ciation between CM and ASD is supported by increasing evidence indicating a strong association between atopic dermatitis (AD), which involves mast cells, and ASD. Activated mast cells in CM and AD could contribute to their patghogenesis, hence inhibiting mast cell activation may have considerable
benefit.