Case report: hydrotherapy as adjunctive therapy of severe pediatric atopic dermatitis treated with dupilumab.

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease with significant morbidity. This report presents the case of a 15-year-old male with severe AD, unresponsive to standard treatments, who showed marked improvement with dupilumab and adjunctive hydrotherapy using Minéraux Beauty Thermal Wa-ter™. Over five years of treatment, the patient experienced multiple infections and hospitalizations, with only limited improvement until the introduction of dupilumab and hydrotherapy. The combination therapy resulted in significant lesion resolution and enhanced skin hydration. This case underscores the ef-ficacy of dupilumab as a cornerstone treatment for severe AD and highlights the potential benefits of hydrotherapy as a safe, cost-effective adjunctive the-rapy. Further research is warranted to explore the synergistic effects of com-bining immunobiological agents with hydrotherapy in managing severe AD.