Combination of PRP, chemical peeling and IPL in controlling Acne – a multimodality approach

Abstract

A common skin condition, Acne Vulgaris, is a disease affecting the pi-losebaceous glands. The common occurrence is on the face, back, and arms, but it can also be present in other areas. The problem with treating acne is the long-term treatment, leading to less compliance and frustration among patients. There are various systemic and topical treatments avai-lable for treating acne. The problem is the long-term treatment and slow results leading to a lack of patient adherence. The other concern is the side effects of these medicines. Various clinical options are being used as an adjunct to other medications or as monotherapy. Platelet-rich plasma is an autologous concentration of platelets. The growth factors released from activated platelets can control the inflammatory process, angioge-nesis, and wound healing. Chemical peels are exfoliative agents that can regenerate healthy skin and have been used to treat acne for decades. In-tense pulse light has an antibacterial ability and controls the erythema. The study evaluated the efficacy of combining PRP, chemical peeling, and IPL in noncompliant patients with topical or oral medication. A com-bination of these three modalities was done in 5 patients in whom tole-rability or compliance with other medications was an issue. There was a significant improvement in all 5 patients. The satisfaction rate of the patients was good. A combination of modalities is an effective and safe way to handle acne. Alone or combined with topical or oral medication, a multimodality treatment in clinics can help patients fight acne better. Larger, randomized clinical trials are needed to support these findings.