Editorial of Issue 2, volume 41, 2023
In this issue, several new data and hypotheses in the vast field of Applied Cosmetology are reported for the readers and in general for the scientific community.
The Superficial Enhanced Fluid Fat Injection (SEFFI technique) has been further investigated by F. Melfa et al. with the characterization of the harvested adipose-derived mesenchymal cells and the introduction in the culture of such cells of the calcium Hydroxyapatite. This co-culture represents a novelty in the realization of extraordinary injectable regenerative anti-age materials presently proposed by the Authors for face rejuvenation.
Kubik et al. present their experimental data on the relevance of the rheology of the different fillers presently available. Heat may play an extremely important role in the rheology and consequently in the efficacy of the injectable fillers. This paper represents a milestone in the fillers engineering in the injectable practice.
De Biasio et al. introduce the possibility of increasing our armamentarium in the oral treatment of androgenic alopecia with vegetal adaptogens. In their randomized double-blind placebo-controlled clinical trial to evaluate the effect of an Annurca apple supplement formula in androgenic alopecia, the Authors show the positive action of the oligomeric procyanidins in hair regrowth in subjects with androgenetic alopecia.
Diffidenti et al. report on their study on the reduction of the fat layer with an appropriate diet associated with non-invasive microvibration produced by spheres of different densities over the area under treatment. The results obtained by the Authors open a new window to the understanding of the pathomechanism of obesity and an interesting new device for the treatment of adipose accumulation in selected areas.
The interesting paper signed by G. Ruggiero and coworkers is bringing our attention to the use of colloidal silver in the treatment of wounds, mainly in the pediatric age. This paper is of great interest not only for the cosmetic outcome of the treatment, which is usually extremely good but also for the critical use of antibiotic cream. In fact, colloidal silver is not included in the list of antibiotics and it is of great interest for the treatment of these kinds of wounds, mainly in the pediatric age.
Dr. Han from South Korea is reporting in his interesting paper a comparative evaluation of the treatment of acne scars with two different needling devices. It seems that both of them are interested in getting final results. The first device is the well-known manual roller with microneedling. The other one is the automatic stamp. It seems that if patients are properly selected, the best treatment will be easily provided by expert dermatology cosmetologists.
Dr. N. Elmahdawi from the United Kingdom is offering our readers an extremely impressive paper, which is a comparative evaluation of different fillers, which have been used in the past and are used presently. In our opinion, this kind of critical revision is extremely helpful for understanding both the value of the present substances, and molecules, which are on the market and the future development of the fillers.
Dr. D. Araya Bruna, from Chile, is offering to our readers an extremely interesting and practical paper on the use of PEGylated HA for expanding the skin to get an optimal substrate for surgical treatment of complicated lesions of the nose. All those who are involved in surgery of the nose know perfectly how difficult it is to find a way to make aesthetic results enough good for the final judgment of the patient. This paper shows a way that could become an example of a new strategy for the best kind of approach to this problem.
In the paper of S. Pallanti and coworkers, we show the excellent outcome of treatment with transcranial magnetic stimulation in subjects suffering from dermotillomania. Dermotillomania is a well-known disorder and it is included in the field of compulsive obsessive disorders. This disorder may become dangerous because sometimes hair which is pulled out is eaten, provoking very uncomfortable clinical situations. This new treatment proposed by the team which is led by Professor Pallanti, seems to be extremely safe and effective for this case and probably for other similar self-injury disorders which may be included in the so-called self-inflicted dermatosis.
In the paper published in this Issue by Dr. A. Yilgor and colleagues from the Turkish team, there is very curious data about a treatment which has become very common over the years, isotretinoin. According to the study, it seems that there are possible damages to the peripheral nerves in the users of isotretinoin according to electromyographical studies. The disorders are not well quantified and are not yet clearly showing data which would make clinical reconsideration on the use of isotretinoin for patients who need it. Nevertheless, it is interesting to note that the feelings of fatigue and dysesthesia, which sometimes are reported by subjects under isotretinoin, could be explained by these studies. Most probably, further evaluations are needed in this field. In any case, this paper is an illuminating paper for all colleagues and doctors, who are prescribers of isotretinoin, which is not yet replaceable with any other kind of drug.
Torello Lotti MD, FRCP (Edinburgh)
Editor in Chief