BEFly Vector Lift: A Vector-Guided Multilayer Facial Volumization Technique Using PEGDE-Cross-Linked Hyaluronic Acid Fillers – A Case Report

Abstract

Facial aging involves bone resorption, fat compartment deflation, ligament laxity, and soft-tissue biomechanical changes. Conventional hyaluronic acid (HA) filler techniques may not address these changes comprehensively and can risk overcorrection or impaired facial dynamics. Vector-based injection approaches have therefore gained interest, though standardized protocols remain limited. To describe the BEFly Vector Lift, a vector-guided, multilayer facial volumization technique using two PEGDE-cross-linked HA fillers, and to report short-term clinical outcomes in a single patient. A 47-year-old female patient (Fitzpatrick skin type IV) with mild-to-moderate mid- and lower-face volume loss was treated in a single session. Deep juxta-osseous support was performed using a high-density PEGDE-HA filler (28 mg/mL, 2 mL total), followed by subcutaneous volumization using a CaHA-enriched PEGDE-HA filler (26 mg/mL, 3 mL total). Outcomes were assessed using static and dynamic clinical photography, patient-reported satisfaction, and safety monitoring over 30 days. No validated outcome scales were used. At 30-day follow-up, contour improvement was noted in the malar, mandibular, and mentonian regions on photographic comparison. Facial expressiveness appeared preserved. Treatment was well tolerated; adverse events were limited to mild transient edema. In this single case, the BEFly Vector Lift produced short-term contour improvement with preserved expressiveness and acceptable tolerability. The findings are preliminary and based on qualitative assessment. Studies with validated outcome measures, longer follow-up, and larger cohorts are needed.