Progressive Lipodystrophy: topical laser treatment with Endolift® procedure using Eufoton® LASEmaR®1500 1470-nm wavelength


  • J. Sigova Pirogov Russian National Research Medical University Moscow Russia
  • D. Kaliterna Poliklinika Poliderma Zagreb Croatia
  • A. Abdelmaksoud Mansoura Dermatology Venerology and Leprology Hospital Mansoura Egypt
  • M. Kamalska Heliodor Swiecicki Clinical Hospital of Poznan Poland


Progressive Lipodystrophy, topical therapy, optical energy, Endolift®, Eufoton® LASEmaR® 1500, laser treatment


Lipodystrophies are a group of rare disorders of diverse aetiology characterised by variable body fat loss. The loss of body fat may affect nearly the entire body (generalised), only certain body regions (partial) or small areas under the skin (localised). Body fat loss can result from underlying genetic defects, autoimmune mechanisms, or drugs. Progressive lipodystrophy is a chronic, inflammatory, degenerative disease of the connective tissue. It leads to the blockage of the circulation and lymphatic drainage, followed by an accumulation of toxins, which promote hyperplasia of the fat cells. As a consequence, connective tissue rigidity promotes skin dimpling or orange skin. This study was designed to evaluate the efficiency of Endolift®, a novel minimally invasive outpatient laser procedure, for the treatment of Progressive Lipodystrophy. 30 women showing cellulite, in the range of 20 to 55 y-o, were enrolled for this study. Patients have undergone a single treatment under tumescent anaesthesia. Treatment was performed using the Endolift® procedure, consisting of the device Eufoton® LASEmaR® 1500. In addition, a 1470-nm wavelength laser was utilised, lead by micro-optical fibres of different calibres directly inside the skin. This treatment aims to destroy and remove degenerative connective tissue and promote neocollagenesis. Optimal results were obtained by 23 patients, 5 had good results, and 2 reported moderate results. No side effect was recorded. Adipocytolysis was performed on 6 patients and we removed 50 to 350 ml of fat. Even after 3 years, 80% of patients maintain significant results. These data show that Endolift® laser treatment represents one of the most effective treatments for removing Progressive Lipodystrophy.


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Author Biography

D. Kaliterna, Poliklinika Poliderma Zagreb Croatia

Dinko Kaliterna, MD,
Ulica grada Vukovara 284d 4. kat Zagreb (Almeria centar)
Tel: +385 1 4828 961



How to Cite

J. Sigova, D. Kaliterna, A. Abdelmaksoud and Kamalska, M. 2023. Progressive Lipodystrophy: topical laser treatment with Endolift® procedure using Eufoton® LASEmaR®1500 1470-nm wavelength. Journal of Applied Cosmetology. 41, 1 (Feb. 2023), 53/57. DOI: