Retrospective Analysis of Asian Nose and Chin Defects Treated with High G’ Hyaluronic Acid

Abstract

Non-surgical rhinoplasty using injectable fillers is gaining popularity as a minimally invasive alternative for nasal reshaping, particularly in patients seeking correction of post-surgical deformities or enhancement of nasal projection. The choice of filler is crucial for achieving optimal aesthetic outcomes and ensuring safety, particularly in high-risk vascular areas. This study evaluates the efficacy and safety of VYC-25L, a high G’ and high cohesivity hyaluronic acid filler, in treating nasal deficiencies in Asian patients. This retrospective analysis included 25 Asian patients treated with VYC-25L for nasal augmentation. Injections were performed using a standardized grid-based protocol with a supra-periosteal technique, emphasizing midline placement and slow, small-volume injections to mitigate vascular risks. Aesthetic outcomes were assessed using a 10-point Visual Analog Scale (VAS) by independent surgeons, while patient satisfaction was recorded via a three-degree questionnaire. Safety was evaluated through the monitoring of adverse events over 12 months. All patients demonstrated significant improvement in nasal projection and contour, with 100% scoring 8 or higher on the VAS at 2 weeks post-treatment. Patient satisfaction was high, with 92% rating the correction as “adequate.” Results remained stable at 3, 6, and 12 months. Minor complications included transient bruising (12%) and a single case of nasal dorsum hematoma (4%), both resolving without intervention. No instances of vascular occlusion, necrosis, or infection were observed. VYC-25L is a safe and effective option for non-surgical rhinoplasty in Asian patients, providing durable aesthetic results with minimal downtime. The grid-based injection protocol enhances standardization and reproducibility, making it a valuable tool for optimizing outcomes. Further prospective studies with long-term follow-up are warranted to confirm these findings.