Chromium allergy. The new view
Keywords:Chromium allergy, Contact dermatitis, Topical hapten, Allergy prevention
Chromium salts, the metal itself and its alloys are potent allergens and common cause of contact dermatitis. It was found that the toxicity have ions of trivalent chromium Cr3+. This form of chromium barely penetrates the skin barrier as opposed to an easily accessible via the contact hexavalent chromium (chromate and dichromates). This last in the body is reduced to toxic Cr3+. Chromium allergy, because of distribution of this metal, is considered a severe disease. The most common are allergy types V and VI. The aim of this study was to assess cosmetic raw materials potentially reducing the dermal bioavailability of chromium salts. We found that the most promising cosmetic ingredients that protect the skin against the penetration of salts of trivalent chromium appear to be hyaluronic acid and lactic acid.