Selected Synthetic and Natural Actives as Inhibitors in Androgenic Alopecia

Abstract

Androgenic alopecia is a common condition that affects Caucasian males in the age range between 20 and 40. A paper discusses briefly pathogenesis of androgenic hair loss in men and the factors affecting its development. The main part of the paper describes selected  actives inhibiting androgenic alopecia and their mechanism of action, recalling the results of their effectiveness testing in vivo. It discusses the widely used  active substances such as finasteride and minoxidil and a range of plant materials used in traditional medicine for potential use in practice. Unfortunately, not for all interesting plants are available results of human efficacy studies.